Ascorbic Acid: Vitamin C Benefits, Sources & Cautions

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Wellness Mama » Blog » Health » Ascorbic Acid: Vitamin C Benefits, Sources & Cautions

Vitamin C has a rich and surprisingly controversial history. On the one hand, science is clear that the body needs it, but the type, dose, and frequency are all up for debate.

When the common cold is making the rounds, many people turn to vitamin C, also known as ascorbic acid, to help ward off illness. Without it, immune system function declines. Studies also show that without adequate vitamin C the lining of blood vessels and membranes of cells deteriorate. It is a big deal!

But, before downing a lot of prepackaged packets of vitamin C (probably with artificial colors and sweeteners), it is important to understand which forms of are most effective and how to safely consume it.

What is Vitamin C?

Vitamin C is a water-soluble vitamin that is needed for many reactions within the body. Humans are not capable of making it internally (most other animals can manufacture it in their livers). Vitamin C is present in many foods, especially brightly colored vegetables like bell peppers and citrus fruits, among others.

Since the human body does not manufacture or store vitamin C, it must be obtained regularly from diet (or supplements). Though low level vitamin C deficiency is common, severe deficiency (also known as scurvy) is rare in modern times.

Vitamin C is a powerful antioxidant, meaning it can help protect the body from the damage of free radicals. On a practical level, this means that it protects cellular health, reduces the effects of aging, and boosts the immune system.

I first learned about the benefits of vitamin C in high school when I had to do a research paper on Dr. Linus Pauling, a Nobel Prize-winning chemist who is considered one of the fathers of biochemistry. He spent much of his career studying vitamin C and even wrote several books on the vitamin’s impact on health. His work provided much of the current understanding of this important vitamin.

How Much Vitamin C Do We Need?

Vitamin C- sources benefits and cautions

Now, things are going to get hairy. The answer is that it depends on who you ask and when.

Modern research is divided and every health expert seems to have a different opinion. Like many aspects of health, the answer is likely that it depends and that it is different for every individual.

For many healthy people, it is likely possible to get enough vitamin C from rich food sources like certain fruits and vegetables. Certain supplements also contain just whole-food sources of vitamin C and can be beneficial for those wanting to slightly increase their vitamin C consumption.

Research shows that those with certain conditions may benefit from supplemental vitamin C as well, sometimes even in the form of an IV. In fact, some doctors are experimenting with high-dose IV dosing to help in recovery from serious illnesses, surgery, and even cancer.

Linus Pauling himself was rumored to take 12,000 mg or more of vitamin C a day (and he lived to 93)! Since up to a third of people are deficient in vitamin C, it can be important to supplement, but the type absolutely matters!

See what I personally do at the bottom of this post, but do your own research and talk to your own doctor to see what is best for you.

Benefits of Vitamin C

Today, even more science backs up the benefits of optimal amounts of vitamin C. Here are the main health benefits of vitamin C according to current medical research:

1. Boosts the Immune System

Perhaps the most well known benefit, and with good reason. Administering extra vitamin C is always part of my cold and flu protocol. Interestingly, this is also one of the more hotly debated benefits. Several reviews of all randomized controlled data showed little or no effect on colds from vitamin C supplementation. Most of these studies looked at small doses or at the effect after the onset of colds.

Other studies showed benefit from larger doses and from taking vitamin C before the onset of illness. Most notably, one study showed a reduction in symptoms and duration of a cold from one 8 gram dose of ascorbic acid on the first day of symptoms. (Fair warning, a dose that big will likely reach “bowel tolerance” and mean diarrhea for a few hours).

What I do: I start each day with the juice of one lemon in water, which yields about 30 mg vitamin C. I take a food-based vitamin C supplement daily. I also take bigger doses of ascorbic acid during times of stress or illness … more on that below.

2. Supports the Brain

A lesser known but equally important benefit of vitamin C (and why it is part of my daily routine).

The brain maintains vitamin C levels even with other parts of the body show signs of deficiency. In fact, the brain often has 100x concentration as the rest of the body and likely for good reason!

Vitamin C helps the brain in several important ways:

  • reduces reactive oxygen species and protects against neural damage
  • promotes the healthy development of neurons and supports the formation of myelin
  • supports optimal neurotransmitter production
  • leads to expression of BDNF (brain-derived-neurotropic-factor)
  • may even help avoid Alzheimer’s Disease according to recent studies

3. Fights Oxidative Damage in the Body

As you are probably already aware, free radicals and oxidative damage are bad news.

Vitamin C is a potent antioxidant that correlates with reduced risk of disease and longer lifespan, likely because of its ability to reduce oxidative damage and free radicals.

Specifically, studies have found that vitamin C is especially effective at reducing damage in the lungs. This is why RDA guidelines recommend higher vitamin C intake for smokers. Ascorbic acid is also sometimes used in conjunction with cancer treatments to help mitigate oxidative damage.

For those of us who (hopefully) don’t smoke or have cancer, a diet rich in vitamin C and some occasional supplements will likely just help keep inflammation at bay.

4. Boosts Mood and Libido

I notice I am generally happier and feel better when I get enough vitamin C. (And vitamin D, but that is a topic for another day). But science supports my anecdotal finding…

Studies link severe deficiency of vitamin C to emotional instability and anxiety. In one study adequate consumption led to a 35% reduction in mood disturbances and increased oxytocin. Yet another study found an increase in libido from 3,000 mg a day supplementation.

Yet another reason to start the day with lemon water!

5. Promotes a Healthy Heart

The jury is still out on this one, but some studies show that diets high in vitamin C seem to reduce the chance of heart disease and stroke. This is logical, since vitamin C is naturally found in fruits and vegetables and consuming enough of these is also great for the heart.

Another study showed that vitamin C may increase HDL cholesterol and reduce small particle LDL. The latest research even shows that this vitamin may reduce arterial plaque and strengthen blood vessels.

6. Boosts Collagen Production and Improve Skin

Internal and topical vitamin C can help increase collagen production and improve skin health.

Vitamin C helps stabilize collagen and improves the connective tissue in the entire body, including the skin and bones. It is widely used in beauty products since it induces collagen synthesis. Studies even show that it may slow the natural aging process by protecting and improving the body’s collagen.

Topical treatments are clinically shown to reduce the appearance of wrinkles, lines, and sun spots. I often mix a little ascorbic acid powder into my face wash to get these benefits. I also make this facial serum for additional skin benefits.

7. Supports the Adrenals

I also increase my intake of “C” when I’m stressed because it is directly used by the adrenals.

Though this tidbit is less well known, vitamin C is necessary for healthy levels of cortisol. It is found in high concentrations in the adrenal glands and can become rapidly depleted during times of stress.

Types of Vitamin C

Vitamin C is naturally found in many foods, and when possible, this is the best and safest way to consume it. As I’ve said before, you can’t out supplement a bad diet, so even if supplements are needed, diet must come first.

A note on vitamin C and when to consume/take it: vitamin C also helps the absorption of iron, so I try to take it with meals where I eat a real food source of iron.

Food Sources

To get vitamin C from food, consume plenty of raw vegetables and fruits like brightly colored bell peppers, citrus fruits, acerola cherry, broccoli, cauliflower, and others. This is just good advice in general but also great for ensuring healthy levels of vitamin C.

As I mentioned, my regular go-to is drinking lemon water each morning.

Food-Based Supplements

Even with the best of diets, getting adequate vitamin C from food can sometimes be difficult or not possible. In fact, it’s one of only five supplements that Chris Kresser recommends supplementing with since it can be so hard to obtain from food.

Unfortunately, heating destroys much of the vitamin content in food, so unless a person is consuming a wide variety of raw brightly colored fruits and vegetables daily (which is difficult in the winter months), supplementation can sometimes be helpful. Studies have also shown that the nutrients in food have declined over the last 50 years, and this includes vitamin C.

What I Take Daily:

I take a food-based C supplement daily because it is a relatively small dose and makes up for nutrients that aren’t present in food anymore. My favorite is this Essential C Complex.

Ascorbic Acid

The least expensive and most-studied type of vitamin C is ascorbic acid powder. I keep a big bag of non-GMO ascorbic acid around for use at the first sign of illness but don’t take it daily. I also mix ascorbic acid into one-time use skin applications like face masks and into my daily cleanser. It loses its effectiveness quickly when mixed with liquid so it doesn’t work as well for topical uses when pre-mixed into big batches.

Liposomal C

This form uses a specialized technology that is said to make it more bioavailable and much less acidic. My kids love the taste of this one and take it willingly so I always keep it around. It also has great reviews for skin health and I’ve been experimenting with making it part of my daily routine along with a liposomal turmeric.

Cautions and Risks

This essential vitamin is water soluble and generally considered safe at doses up to 2,000 mg a day, according to the Mayo Clinic. At doses larger than that, it can potentially be problematic. Diarrhea is the most common side effect. At extremely large doses, vitamin C may also carry the risk of increasing the likelihood of kidney disease. Pregnant women should also not take doses above the recommended daily amount as it may cause problems for baby.

This article was medically reviewed by Dr. Scott Soerries, MD, Family Physician and Medical Director of SteadyMD. As always, this is not personal medical advice and we recommend that you talk with your doctor.

What do you think about vitamin C? Do you take it or try to obtain it from food?

Sources
  1. Douglas RM, Hemilä H. Vitamin C for preventing and treating the common cold. PLoS Med. 2005;2(6):e168.
  2. Hansen, Stine Normann, Pernille Tveden-Nyborg, and Jens Lykkesfeldt. “Does Vitamin C Deficiency Affect Cognitive Development and Function?” Nutrients 6.9 (2014): 3818–3846. PMC. Web. 29 Mar. 2018.
  3. Zandi PP, Anthony JC, Khachaturian AS, et al. Reduced Risk of Alzheimer Disease in Users of Antioxidant Vitamin SupplementsThe Cache County Study. Arch Neurol. 2004;61(1):82–88.
  4. Douglas RM, Hemilä H (2005) Vitamin C for Preventing and Treating the Common Cold. PLoS Med 2(6): e168.
  5. Sebastian J. Padayatty, Arie Katz, Yaohui Wang, Peter Eck, Oran Kwon, Je-Hyuk Lee, Shenglin Chen, Christopher Corpe, Anand Dutta, Sudhir K Dutta & Mark Levine (2013) Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention, Journal of the American College of Nutrition.
  6. Suh, Sang-Yeon et al. “Intravenous Vitamin C Administration Reduces Fatigue in Office Workers: A Double-Blind Randomized Controlled Trial.” Nutrition Journal 11 (2012): 7. PMC.
  7. Aguirre, Rene, and James M. May. “Inflammation in the Vascular Bed: Importance of Vitamin C.” Pharmacology & therapeutics 119.1 (2008): 96–103. PMC.
  8. Crisan, Diana et al. “The Role of Vitamin C in Pushing Back the Boundaries of Skin Aging: An Ultrasonographic Approach.” Clinical, Cosmetic and Investigational Dermatology 8 (2015): 463–470. PMC.
  9. Carr, Anitra C., and Margreet C. M. Vissers. “Synthetic or Food-Derived Vitamin C—Are They Equally Bioavailable?” Nutrients 5.11 (2013): 4284–4304. PMC. 

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Katie Wells Avatar

About Katie Wells

Katie Wells, CTNC, MCHC, Founder of Wellness Mama and Co-founder of Wellnesse, has a background in research, journalism, and nutrition. As a mom of six, she turned to research and took health into her own hands to find answers to her health problems. WellnessMama.com is the culmination of her thousands of hours of research and all posts are medically reviewed and verified by the Wellness Mama research team. Katie is also the author of the bestselling books The Wellness Mama Cookbook and The Wellness Mama 5-Step Lifestyle Detox.

Comments

158 responses to “Ascorbic Acid: Vitamin C Benefits, Sources & Cautions”

  1. Kristin Avatar
    Kristin

    I noticed in your post about avoiding Group B Strep during pregnancy you suggest taking 2,000 mg of Vitamin C everyday. The link you have in that post is for a form of asorbic acid Vitamin C. I ordered the Pure Radiance Vitamin C (based on this Vitamin C post)–would you still recommend taking 2,000 mg of this type? That would be 16 pills a day! Lots of pills and money!

  2. Angela Avatar

    I was wondering what kind of vitamin c you would recommend for 6 month.

  3. Sunny Avatar

    I’m thankful that you write about and research all this stuff so that I don’t have to, but I seriously don’t know how you do it all without losing your sanity. It’s so much!

  4. James Brookman Avatar
    James Brookman

    Your reference to Dr. Albert Szent-Gyorgi is incorrect.

    My father knew Linus Pauling and Szent-Gyorgi told Dr. Pauling that he took at least 1,000 mg of supplemental vitamin C a day. This is noted on the Linus Pauling site.

    Further, a comprehensive study was published, “Synthetic or Food-Derived Vitamin C—Are They Equally Bioavailable?” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847730/pdf/nutrients-05-04284.pdf) that showed no difference between supplemental so-called “synthetic” vitamin C and vitamin C in food.

    There is nothing wrong with synthesizing natural-identical nutrients. The body synthesizes billion of molecules every second, including a couple of vitamins. Synthesis is just simple natural chemistry.

    You’re spreading fear-based misinformation that is contrary to published science.

    You could be helping people be healthier, but you’re spreading the nonsense that so-called “whole-food” vitamin companies spread, while they deliver nutrient potencies that are confirmed in thousands of published studies to not produce optimal effects while costing about 12 times more than the USP-type nutrients that over 300,000 studies show to be safe and effective.

    You should be studying the published medical literature, rather than depending on referring to commercial sites, like Radiant Life, that have an agenda, so they twist the facts to sell their products.

    1. mark speed Avatar
      mark speed

      published science!!
      published medical literature!!

      James Brookman it is you who needs to re educate your self.
      published science & published medical literature are the dis info scum, owned &/or sponsored by corporations soley concerned with profit margins, the info they publish is controlled to suit them and the trail leads to the big medical-pharmaceutical system, their vital income stream based on keeping us all ill and diseased would dry up and the system collapse. As this is the biggest and most profitable industry in the world, this cannot be allowed to happen.

      The foods we eat is crap, WE ARE ORGANIC BEINGS, WE NEED ORGANIC FOODS TO FEED OUR ORGANIC BIOLOGY, WE ARE NOT SYNTHETIC BEINGS! SYNTHETIC PRODUCTS ARE NOT NEEDED (only needed by the systems need to keep us in illness to create trillions in profit) WHY THE HELL DO PEOPLE SCOFF AT ORGANIC AND NATURAL FFS (idiots), Organic means not grown with chemical sprays, pestesides & crap , it means grown how its ment to be grown, Its no good to wash fruit and veg to remove residue! its all been sprayed and poisoned from seed to sprout to fully mature, non-organic produce contains toxins in every single cell so washing is pointless.

      The FDA for instance allow one of the most toxic additives known to man – aspartame- to be included in a very high number of food products even tho evidennce shows its 3 types of toxins in one but the third toxin wen in the body then transforms into famaldahyde!!!
      So published science & published medical literature serve the money makers and they also change their findings every 5 minutes so what was so called fact last year was wrong, its now this fact bla bla bla.

      You are spreading false lies that help to profit the upper elite. by all means please carry on with your syntheticness, im sure you will most likely develop some nasty cancer that ‘they’ cant cure (but they can-but wont). All their crap is coming to light now and common sense is all around us if you open your eyes.

      1. Jesse Avatar

        There is very little money to be made via ascorbic acid. In fact, promoting natural vitamin C over “synthetic” (sic) probably helps the profit margins of a number of supplement manufacturers. I happen to stand by published research on this topic. There is certainly nothing wrong with whole food vitamin C, but please don’t discount ascorbic acid and the contributions of Linus Pauling et al.

  5. Michelle Avatar
    Michelle

    I am a long time reader and have been so inspired and enlightened by your blog over past years! I have a sort if off topic issue that I am desperate for any knowledge you may have to share! I am a first time mom and so gratefully breastfeeding my sweet 9 wk old. I have been dealing with, thrush for 7 wks and mastitis for 4 weeks which has now developed into a very large abcess that has been aspirated several times now. I have devoured every bit if knowledge on how to treat naturally and tried everything I can find to do with the topic and also finally breaking down to take not one, not two but now three differant antibiotics. I am being told by my doctors and breast surgeon that the next form of treatment will be surgery or a catheter placed to help heal the infection. However this may end up resulting in me not being able to continue breast-feeding as they may have to dry up my milk should a milk Fissure develop due to the procedure . I know this is a lot of information to throw out but I have been looking at this post in order to’s possibly see if I need to switch vitamin C methods! I would love love love to first of all know how much of this more natural form of vitamin C can I safely take while nursing and fight this infection to the best of my ability. Also if you have any other advice on treating a staff infection/breast abscess for a nursing mama. Thank you so much again you’re such a blessing and I love the way you approach the world and share it with all of us.

    Michelle

    1. Katie - Wellness Mama Avatar

      I’d personally take more vitamin C if I was fighting that type of infection, as the risk to baby would be less that the risk from the infection. Is there a naturopathic doctor in your area you could consult about ways to help build up your body to fight the infection. my sister in law had a similar infection and abscess and it was awful. I know she soaked the breast in warm epsom salt and baking soda water several times a day to help stop the infection. I think she also used cold laser therapy and an herbal poultice a few times a day.

  6. Natasha Avatar

    Is it safe to take the vitamin C you recommended from Pure Radiance while pregnant?

  7. Paula Avatar

    All I can say is that since I started making and taking my own sodium ascorbate, which is pure non gmo derived ascorbic acid plus half the ratio of non aluminium processed bicarbonate of soda in distilled water, my health has improved. I have M.E. which is a really debilitating condition of chronic low energy.

    First of all, my skin tone improved, then I noticed that my gums stopped bleeding. I had had mild gingivitis since my pregnancy 20 years ago, every time I cleaned my teeth. After only a few days of taking approximately 1 gram of C 3 times a day (sometimes 4) it went completely. Now some people understand that gingivitis can be caused by a vitamin C defficiency, yet, my diet was full of organic peppers, tomatoes, and many other sources of vitamin C (I eat a LOT of salad) in addition to 6 x 1g tablets of buffered vitamin C daily. So I must have had a defficiency.

    People had told me that the form of it was important before but because they were all pushing out the lipospheric/liposomal form because it’s the new trend and very expensive, or tricky to make, I dismissed it, thinking I must be getting enough vitamin C taking this much daily.
    But guess what, it can’t have been getting absorbed properly in the tablet form. Aside from the gums and teeth feeling stronger, I’ve also toned up much more in my muscles and am able to build them much easier, and I feel much stronger, generally, with a bit more energy.

    When I first drank the solution it felt like liquid light spreading out from my tummy, very uplifting, and I actually feel and I think look younger. I don’t use vitamin C serums on my face but I have much more tone for my age, and people say I look younger now than I used to. So I say the sodium ascorbate version is really working. It’s cheap and effective, and so long as your diet contains all the othe rmicronutrients or you can supplement then I don’t think you need to worry too much. I also take a probiotic an hour or so after one dose of C per day just in case this neutral ph version is destroying some of the good gut bacteria.

    Another thing I’ve noticed is that I feel less need to snack in between meals because my energy levels are more stable. This could be to do with more glutathione availability, or just a stabilising in blood sugar. I’ve never had much of a sweet tooth but now I don’t crave savoury carbs as much either, or if I do, I’m satisfied with much less. I’ll normally have a boiled egg or a small handful of sunflower seeds and that seems to do the trick. I’m hoping to finally loose a few stubborn pounds, now. Fingers crossed! 🙂

    1. Suzanna Avatar
      Suzanna

      Hi, could I please get your recipe? I also have chronic fatigue, epstein barr issues and my gums are receding like crazy though I have tried many things. My muscle tone is not very good anymore because of the fatigue I don’t exercise enough. I do take the Vitamin c chewable flavored powders but notice they hurt my tummy. Of course I also have a compromised gut. And I eat healthy. Very healthy! I would be so grateful for this recipe. Thank you!!

      1. Inger Grape Avatar
        Inger Grape

        Dearest Suzanna,
        Some of your issues could be helped by bouncing on a rebounder (mini-trampoline). It’s effective at even very low levels of exertion, it’s amazing for the lymph and immune system, and it’s just the most important tool for one’s health! It’s such an easy and pleasant way to get exercise, and it works in even bits and pieces, doing 2 minutes here and 5 minutes there. It transformed my life. https://wellnessmama.com/13915/rebounding-benefits/

  8. Mike Avatar

    Does anyone get really gassy with Vitamin C? I’ve tried the regular ascorbic acid and sodium ascorbate and even at a small dose (less than half a teaspoon) I am gassy all day. I’m taking it on an empty stomach, in between meals too!

    1. Christina Avatar
      Christina

      Try taking it with a pinch of baking soda. What I like to do is mix my daily value of Vitamin-C in a water bottle (non-metallic), with water, the juice of half a lime and a pinch or two of baking soda. I sip a little all day long.

      1. Mike Avatar

        I’ll try that. I just figured that the sodium ascorbate would be buffered enough to not cause stomach upset.

  9. mary Avatar

    as i am nursing, i decided to give vitamin c a try for my general health; especially my adrenal health as i have issues with stress management and sleep. i just got the capsule bottle. it says 120mg while you take 2,000 mg – that’s a lot. what is your take on this?

    thanks!!!!!
    :)mary

  10. curtis Avatar

    There is a lot of misinformation out there about Vitamin C Complex and ascorbic acid. I would encourage you and your readers to go over to the vitamincfoundation.org and read up for yourselves, if you haven’t already. On the forum there is a spot dedicated to the conversation over complex and ascorbic acid. For the record – I have no connection/affiliation with this site or anything Vitamin C related.

  11. Dee Avatar

    I wanted to add that people may want to be careful with high doses of supplemental vitamin C in any form. If you have a tendency towards oxalate problems (such as kidney stones, interstitial cystitis, etc.) vitamin C can worsen them, due to it being able to convert to oxalate in the body.

    1. brian Avatar

      I agree with oxalates….

      I guess thats the case with me… after take vit c i constantly go to the bathroom for urine galore

      and my left side hurts a bit?

  12. Anne Avatar

    Just received my Vit. C. Purchased the one that Katie recommended.
    Katie…do you take this everyday all year round? If yes how much do you take each day?
    I too have Hashimotos and I am hoping this will be a beneficial supplement to add to my routine.
    Is it true that taking this with collagen makes them both work more efficiently in the body?
    Thank you!!

  13. Amy Avatar

    I take lipo spheric Vit C by LivOn Labs. I also use camu camu if I’m making a smoothie 🙂

  14. christine Avatar

    I learnt about vitamin C when I was a teenager. My dad read about Linus Pauling and since then I have been taking vitamin C. (I am 59 soon) I take up to 20 GRAM ascorbic acid daily and if there is a medical problem I will go to bowel tolerance level. My son, however, finds the ascorbic acid hurts his stomach but I have never had a problem with it. I am grateful to say that I am healthy, fit and do not need any chronic medication. I follow the advice of the Orthomolecular doctors (started by Linus Pauling) You can read about them on their website (orthomolecular.org)

    1. Lisa Avatar

      After having a stroke at the age of 56, I have read everything I can read about Vitamin C and I take a minimum of 3000 mg of liposomal vitamin C. lysine and proline daily. I also supplement with a product called Ascorcine 9 for cardiovascular support. These supplements heal your arteries and remove the lipids from the vessel walls. My triglycerides went way down as did my cholesterol. I found out about this product on the Vitamin C foundation’s website. Read all about Linus Paulings cure for heart disease.

  15. Nancy Avatar

    I looked at the Camu Camu powder and it made me wonder if harvesting this, and it’s’ growing popularity, will have an ill effect on the Amazon region and it’s people?

  16. Kathleen Avatar

    Hi Katie, I didn’t realize not all Vitamin Cs are created equally & a few months ago I bought Vitamin C crystals Ascorbic Acid to make your DIY Vitamin C serum – which I love. I have a big jar of it so I hate to dump it for real Vitamin C…do you think used externally this is okay? Or is it not effective & I should be using real C in my serum? Thanks.

  17. Cassie Avatar

    I don’t know if you’re aware of this but absorbic acid, and often times vitamin c, when listed in the ingredients (example in coconut water) often comes from corn! I only know this because I have a severe corn allergy and react severely to almost anything listed as vitamin c or absorbic acid.

    Just something interesting to keep in mind.

  18. tarah Avatar

    Hey Katie, I have a question. You provided a link to a PubMed study measuring the declining nutrition in 43 different types of produce. One of the things they measured was ascorbic acid. But you said that ascorbic acid isn’t found in nature, so how can they isolate it and measure it in this study?

    Thanks, this article was helpful. I’m trying to get my mom to quit drinking so much “Emergen-C” packets.

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