How Thyroid Disease Affects Pregnancy and Fertility

Katie Wells Avatar

Reading Time: 7 minutes

This post contains affiliate links.

Read my affiliate policy.

How Thyroid Disease Affects Pregnancy and Fertility
Wellness Mama » Blog » Health » How Thyroid Disease Affects Pregnancy and Fertility

There aren’t many things I can say I’m an expert at in this world. In fact, the short list would include accidentally killing house plants and procrastinating until I have 8 loads of laundry to fold.

But there are a couple of other things I’m pretty close to expert status at after years of navigating them: pregnancy and thyroid disease. With about 5 combined years of pregnancy and almost twice that many years since my thyroid diagnosis, I’ve learned the hard way how to navigate them both… especially together.

Thyroid Disease + Pregnancy

Pregnancy can be such a wonderful and joyful time, even though it has its struggles.

But there’s another side of pregnancy that can be heartbreaking and devastating…and that is infertility and loss. I recently shared a post about thyroid disease and the autoimmune condition often responsible for causing hypothyroidism, called Hashimoto’s thyroiditis. Not only can it cause debilitating fatigue, anxiety, hair loss, inability to lose weight, and so much more — it can also cause infertility and problematic pregnancies.

This is something that the conventional medical community acknowledges, but there don’t seem to be many good resources for pregnant women with thyroid disease. During pregnancy and postpartum, our hormones go through the ringer. This isn’t a bad thing by any means, but because of the overwhelming amounts of hormonal changes, it can trigger an adverse thyroid reaction.

An undiagnosed or not properly managed thyroid problem can also lead to various complications with pregnancy and birth. In fact, untreated thyroid disease increases the chances of premature birth, preeclampsia, miscarriage, low birth weight, anemia, and even stillbirth.

Thyroid Problems: What to Look For

It took me years to get properly diagnosed, and I’m incredibly grateful that my children are healthy and my pregnancies were just fine. But, I also wish I’d known the signs and what to ask the doctors to test.

Thyroid disease isn’t something to mess around with, especially before and during pregnancy. Anyone who even suspects thyroid disease should get tested, preferably before pregnancy or as soon as possible. Ask to see the results and make sure the doctor is using the most up-to-date references. Depending on the doctor’s school of thought, they may be using outdated reference ranges.

5 Lab Tests to Request

Dr. Izabella Wentz, creator of The Thyroid Secret documentary series, recommends these five tests to help pinpoint a potential thyroid problem:

  1. Thyroid Stimulating Hormone (TSH) — This is the pituitary hormone that measures the level of thyroid hormone in the blood. When it is low, that may be a sign that the level of thyroid hormone being made from the thyroid gland is too high. When TSH is too high, it may be a sign that the level of thyroid hormone being made from the thyroid gland is too low.
  2. Free T3/Free T4 — Measures the level of active hormones in your blood.
  3. Reverse T3 — This will help determine whether you have hyperthyroidism or hypothyroidism. It tends to be low in hypothyroid cases and high in hyperthyroid cases. Reverse T3 measures the amount of inactive T4 in the body and is most helpful for diagnosing an underactive thyroid.
  4. Thyroid Peroxidase Antibodies/Thyroglobulin Antibodies (TPO/TG Antibodies) — Measures the antibodies and is a great test to spot the condition forming years before it manifests through the TSH test.
  5. Thyroid Ultrasound — Especially recommended if your doctor suspects abnormal growth or if you have a known thyroid condition.

If any of these labs come back out of the normal range, work with your doctor to establish some best practices to get them back within normal range. Sometimes this might look like medication, and other times, it calls for lifestyle interventions like diet, supplementation, and removing toxins from your life.

The Gene Factor

There is a gene mutation known as the MTHFR mutation that can also have a really big impact on pregnancy. A lot of doctors are not familiar with the research on this gene and don’t recognize this mutation as a risk… but it is!

Countless women have this gene mutation and here’s why it’s worth testing. There are now even at-home tests that test for this mutation.

Folate vs. Folic Acid

One key part of the MTHFR gene mutation is the inability to methylate folate correctly (especially in the synthetic form of folic acid). So as the folic acid comes into the body, it doesn’t get processed and absorbed. Pregnant women need 400 mcg of folic acid per day because it helps prevent birth defects and is essential for baby’s growth. However, if you’re a woman who has this gene mutation, you’re not going to be able to absorb folic acid properly and need to be taking the real version of folic acid called folate.

It’s a real tragedy that babies aren’t getting the right nutrients and suffering the consequences simply because doctors are missing the signs that say these moms need to be on a different form (the real form!) of folic acid. Personally, even before finding out that I had an MTHFR mutation, I chose a prenatal with a natural form of folate… just in case.

Those with this mutation should consider removing folic acid from your diet completely. It is the synthetic version of folate and tends to hide in processed foods and enriched flours. It is better to opt for healthier alternatives like veggies rich in folate and low-glycemic fruits such as blackberries. Going gluten-free is another great way to avoid folic acid.

I have great options in my Wellness Mama Cookbook that you and your family might enjoy.

Thyroid Flares During Pregnancy

The most common form of hyperthyroidism in pregnancy is Graves’ disease. In fact, 1 in 1500 women will be affected during their pregnancy. This occurs when there are really high hCG levels in the body.

According to the American Thyroid Association, the most common type of hypothyroidism is caused by the autoimmune disease Hashimoto’s. The ATA states, “Approximately, 2.5% of women will have a slightly elevated TSH of greater than 6 and 0.4% will have a TSH greater than 10 during pregnancy.”

Both of these conditions can have adverse impacts on both mom and baby, so it’s important to address them. Taking ownership of your health during pregnancy is essential for both of you. If you’re currently struggling with infertility or have suffered from miscarriage(s), take hope that there are proven steps you can begin taking to better your health and improve your chances of conceiving.

Addressing Thyroid Triggers

One big step toward thyroid health is simply addressing triggers that could be causing the thyroid to get out of line.

Leaky Gut

Leaky gut, or intestinal permeability occurs when the body is unable to process food and nutrients the right way. In essence, the gut becomes leaky, and food and other bacteria slip through the cracks triggering digestion and absorption issues. If you’re a science lover like me, you may find this article really helpful for explaining the technicality of intestinal permeability.

Nutrient Deficiencies

This is a big one. Depending on diet, it is easy to be really low in some essential nutrients like iron, magnesium, selenium, and vitamin D. Gut problems can also decrease the body’s ability to process these nutrients effectively.

If there’s a problem in the gut, then no matter how much we consume these supplements or eat nutrient-rich foods, the body won’t be able to snag all the goodness from them. This is especially important to address during pregnancy since there is an increased nutrient demand.

Adrenal Dysfunction

Stress is a huge component of overall wellbeing. The ability or inability to handle stress can directly affect health. Our bodies release cortisol based on our reactions to circumstances and our environment. Our bodies can release too much or too little based on what it thinks it needs. When cortisol dries up, we enter a state of adrenal fatigue.

Symptoms like low blood pressure, decreased sex drive, mild depression, and feeling overwhelmed or indecisive can all stem from adrenal dysfunction.

Food Sensitivities

Ever feel swollen or bloated after eating? Or get an upset stomach or experience an acne breakout even though you’re well past the teenage years? All of these symptoms can indicate that your body is sensitive to whatever you just ate.

Food sensitivities like gluten, dairy, and soy are quite common, so try removing them from your diet and get ready for a huge improvement in the way you feel. Gluten can even cause leaky gut, so for those trying to heal intestinal permeability, eliminating gluten is a must.

Blood Sugar Imbalance

This one goes hand in hand with supporting the adrenals. When we balance blood sugar, it can decrease anxiety and thyroid antibodies. Dr. Wentz recommends reducing refined carbohydrates and ramping up the good fats and proteins. Proteins and good fats tend to keep you satisfied longer and provide more energy for you to absorb.


A toxic buildup is also common in people struggling with thyroid disease. There are some things like the air we breathe or the water we drink that we can take steps to improve. Perhaps it’s time to clean out the old beauty and cleaning products filled with harmful ingredients and switch over to a more natural way of doing things. Here are some great baby steps to take toward this goal.


Underlying infections and bacterial overgrowth like Candida are important to address, especially for those who are having trouble conceiving. There are many natural products that can help eradicate gut infections, but I recommend following a well-researched program and working with a trained practitioner. This is especially important for those who are currently pregnant!

Iodine During Pregnancy?

In the functional world of medicine, whether or not you should take iodine is a hot topic. Some people say you need it for proper thyroid function, while others staunchly oppose it. Depending on where you live in the world, you may not need additional supplementation.

During the first 10-12 weeks of gestation, the baby is completely dependent on mama for thyroid hormone. After that, the little one needs iodine in order to produce its own hormone. The World Health Organization recommends 250 µg/d of daily iodine intake, however, in the US, our diets usually provide enough iodine so check with your doctor to see if you need additional supplementation.

Find a Doctor Who Understands the Thyroid

This probably goes without saying, but finding a doctor who understands thyroid disease and how it affects pregnancy is vital for the conceiving process (for those with infertility) and throughout pregnancy. Look for someone who is knowledgeable about the thyroid and open to lifestyle interventions alongside necessary medications if they’re needed.

If there is one thing I’ve learned in all these years of managing pregnancy and thyroid disease together, it is this:

You are your own advocate, and you are your baby’s advocate. If you suspect something is wrong, be the voice for yourself and your child. Ask questions, do research, and don’t be afraid to stand up for yourself.

More Thyroid Help (for Pregnancy & Conception)

Wading through all the information about the thyroid and pregnancy can feel a little overwhelming. You’re not alone, and I want to share one resource I wish I’d had years ago. You’ve probably heard of a documentary series called The Thyroid Secret, but just in case you haven’t, it has information from Dr. Izabella Wentz and dozens of the top thyroid experts. There’s an entire episode dedicated to fertility and the thyroid so whether you’re trying to conceive, currently pregnant, or struggling with postpartum thyroiditis, this series will be very helpful.

This article was medically reviewed by Dr. Shani Muhammad, MD, board certified in family medicine and has been practicing for over ten years. As always, this is not personal medical advice and we recommend that you talk with your doctor or work with a doctor at SteadyMD.

Do you or someone you know suffer from infertility or high-risk pregnancies? I’d love to hear your thoughts in the comments!

Katie Wells Avatar

About Katie Wells

Katie Wells, CTNC, MCHC, Founder of Wellness Mama and Co-founder of Wellnesse, has a background in research, journalism, and nutrition. As a mom of six, she turned to research and took health into her own hands to find answers to her health problems. is the culmination of her thousands of hours of research and all posts are medically reviewed and verified by the Wellness Mama research team. Katie is also the author of the bestselling books The Wellness Mama Cookbook and The Wellness Mama 5-Step Lifestyle Detox.


15 responses to “How Thyroid Disease Affects Pregnancy and Fertility”

  1. Kayleigh Avatar

    I have had 3 miscarriages in the last 2 years of trying to concieve. I recently found out that I have a thyroid problem and have been put on thyroid medicine. We are so hopeful for the next pregnancy and praying I’ll be able to keep it now that I’m on the medicine. Thank you for this article! Very helpful and insightful!

  2. Shannon Avatar

    Great article! I have a similar story and had undiagnosed symptoms until I started seeing a naturopath/midwife. I tend to get Graves Disease during pregnancy and struggle with gaining enough weight, sleeping, anxiety, etc. For care we focus on gut health- lots of good probiotics. The herb I’ve found the most helpful is lemon balm. I’ve been drinking 1-2 cups daily and it makes such a difference to my symptoms, especially sleep. I normally have great difficulty sleeping when pregnant, but the lemon balm tea is amazingly effective. I don’t know if it’s effective for hypothyroidism, but for hyperthyroidism it is wonderful.

  3. Nicolette Avatar

    When you ordered from, which test did you choose? I looked at what they offer, and didn’t see anything for the MTHFR gene. Wondering which one to go with.

  4. Kay Avatar

    I know quite a few people diagnosed with hypothyroidism, who have used an organic, high-selenium yeast successfully. Doing a lot of research on selenium (my 9-month old was diagnosed with liver fibrosis due to a genetic disorder), it turns out that selenium is also really important for the liver as far as cancer and tumors (not just the thyroid). We are just beginning to scratch the surface on the importance of nutrients/trace minerals for thyroid issues like iodine and selenium, but I am a believer in the organic selenium yeast sourced products. Maybe you could do an article on organic selenium and the liver? You can inbox me for more info on the blood test levels.

  5. Erin Avatar

    I have type 1 diabetes. Knowing that I wanted to conceie, my endocrinologist tested antibody levels in my thyroid, which were positive, and I was diagnosed with Hashimotos. She pushed Levothyroxin, which I absolutely hate. I follow a strict organic, Paleo diet. Is there anything else you recommend to improve thyroid function?

  6. Tiffany Avatar

    I was tested by my PCP for the MTHFR Mutation and found I am Double Heterozygous, from my father’s side. I only know it’s from my Father’s side, because my Mom took the 23 and Me test and she does not have the MTHFR Mutation.
    I take the methyl form of folate and B12. I also have a Vit D deficiency, which runs in my Mom’s family. My thyroid has been tested twice and has had “normal” results. I definitely feel like I have adrenal and/or thyroid issues because I suffer from fatigue, weight gain, depression and anxiety. Also, my partner and I have been TTC for nearly 2 years. I am 39 yrs old and after 6 mos of testing, I am in my first IUI cycle. Any recommendations for natural supplements that might help with my symptoms of fatigue, weight gain, infertility, depression, and anxiety that would be safe while TTC and during pregnancy?

  7. Chrisann Justice Avatar
    Chrisann Justice

    My youngest is 16 now but I’ve often wished I could go back in time and re-do the pregnancies with everything I’ve learned about my body and my health. I had severe morning sickness with all five pregnancies. It was the very worst with my first as I threw up till the seventh month. I felt nauseous the entire pregnancy and it wasn’t only in the mornings. It was 24/7. It was more than just nausea though. I was extremely weak, depressed and sensitive to odd things like music. I love music but I couldn’t bear to listen to it when I was at my sickest points. So, fast forward to years after the pregnancies and everything I’ve learned about myself. I was diagnosed with rheumatoid arthritis when my youngest was 3. I have been able to go into remission by completely eliminating dairy. Ten years later I found out I had a thyroid issue and was also celiac. My mother had a problem with her thyroid from the time I was a child and I had suspected that I did and asked doctors to test me repeatedly over the years. I finally found out about the more in depth testing that you need to request and found a doctor that would do it. My symptoms were no worse than they had been for years so I suspect I had been suffering with low thyroid all along. I also found out that I have problems with my adrenals. I now eat 100% gluten and dairy free, take supplements to support my thyroid and adrenals and feel healthier than I did at 20. I’m 51. So, I know that no one can answer this question from my past but what I’m wondering is if you know of women with thyroid and adrenal problems that suffer the way I did when I was pregnant. Do you feel that there is a link? For some reason it’s important to me to know if my suffering could have been avoided. Whenever I meet women that are suffering the way I did I desperately wish I had some sound advice. I have a sister that’s a midwife and I would love to pass on yours and others observations regarding this.

  8. Kat Avatar

    Katie, do you have any resources for adrenal and thyroid maintenance while BREASTFEEDING? I am attemtping to do some research regarding traditional herbs and some adaptogens taken postpartum. I have a 6 month old son and my recent checkup at the doctor was a total bust (she didn’t give me any advice regarding my low BP or adrenal fatigue synptoms, so I had to schedule a naturopath meeting). Most traditional doctors simply do not know how to approach postpartum stress and fatigue with natural means.

    Can you please share what herbs and supplements you took during pregnancy and/or postpartum? Thanks!

  9. Tyler Avatar

    Wow, what a great in-depth article. Love how many references and links you put in this. It is amazing that in some circumstances a lot of what you need to know, in terms of asking for specific tests or knowing exactly what kind of doctor you might want to talk to about this, a lot falls back on the person themselves. There are times when we just think that a person of a certain status will know exactly what to tell us. But knowing our basics and keeping up to date with all the new research that might be pointing to a different direction can be overwhelming and/or stressful. You laid all the basic need to knows spectacularly and directions on how to find out more.

    Thank You!

  10. Maria Avatar

    I lost my son 7 months ago Due to an overlooked preeclampsia te OB replacement didn’t notice he didn’t grow anymore the last month. While I asked her continuously about my son’s weight she said everything was fine.5 days earlier I had the feeling something was off and asked for an appointment but I had 2 waits 3 days. He died of placental abruption with 39.5 weeks, I got that day HBP and I never had any symptom of preeclampsia only I was swollen in my feet she said again it was normal. When I come to the hospital I had to wait and He died 5 minutes before he was out. Later I joined the preeclampsia organisation to learn more. They advised me to take a look at my b12 and thyroid. When I got my results my B12 was very low and my Thyroid was working fast. Now I am in hand of an internist and he is giving me shots and a treatment for the B12 shortage. He made more exams I will hear about it soon.

Leave a Reply

Your email address will not be published. Required fields are marked *